Abbr. Expansion Instances Papers News
RBD receptor-binding domain
Antibodies from eggs of hens (immunoglobulin Y; IgY) that were administered the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein were developed for use as nasal drops to capture the virus on the nasal mucosa.
190 184 6
VOC variants of concern
SARS-CoV-2 variants of concern (VOCs) have caused a significant increase in infections worldwide.
185 174 11
ACE2 angiotensin-converting enzyme 2
The nCoV-19 uses its spike glycoprotein receptor to bind to the host cell angiotensin-converting enzyme 2 (ACE2) sites to launch a combination of events leading to server acute respiratory syndromeangiotensin-converting enzyme 2 (ACE2) sites to launch a combination of events leading to server acute respiratory syndrome.
117 113 4
RCTs randomized controlled trials
Methods Published randomized controlled trials (RCTs), cohort studies, and case-control studies that evaluated the VE against VOC (Alpha, Beta, Gamma, Delta, or Omicron) were searched until 4 March 2022.
21 20 1
RR relative risk
Random effects model using Mantel–Haenzeal method was used to pool relative risk (RR).
20 20 0
CIs confidence intervals
Pooled estimates and 95% confidence intervals (CIs) were calculated using random-effects meta-analysis.
17 17 0
FDA Food and Drug Administration
Therefore, the Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) for the use of certain therapeutic agents because they have shown remarkable clinical outcomes.
16 10 6
NTD N-terminal domain
Structural analyses show that the P86 clone targets epitopes that are conserved yet unclassified on the receptor-binding domain (RBD) and contacts the N-terminal domain (NTD).
14 12 2
LFIA Lateral flow immunoassays
Protection estimates were about 85% protection in two overlapping meta-analyses, while in several larger studies increased protection with higher antibody levels was observed.Lateral flow immunoassays (LFIAs) detecting anti-SARS-CoV-2 IgG are a cheap, readily deployed technology which has been used on a large scale in population screening programs.
8 7 1
VSV vesicular stomatitis virus
Here, a replication-competent vesicular stomatitis virus (VSV) vectored recombinant COVID-19 vaccine was constructed and evaluated in BALB/c mice and Syrian golden hamsters.
6 5 1